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Publication : The tropomyosin mRNAs of mouse striated muscles: molecular cloning of beta-tropomyosin.

First Author  McInnes C Year  1988
Journal  Biochim Biophys Acta Volume  951
Issue  1 Pages  117-22
PubMed ID  2461223 Mgi Jnum  J:25072
Mgi Id  MGI:72785 Doi  10.1016/0167-4781(88)90031-0
Citation  McInnes C, et al. (1988) The tropomyosin mRNAs of mouse striated muscles: molecular cloning of beta-tropomyosin. Biochim Biophys Acta 951(1):117-22
abstractText  The nucleotide sequence corresponding to the complete coding region and much of the 5' and 3' untranslated regions of the skeletal muscle-specific mouse beta-tropomyosin mRNA was determined from overlapping cDNA clones isolated from a library of recombinants in pBR322. When one of these was used as a probe to detect tropomyosin mRNAs expressed after fusion of mouse myoblasts in culture, species were detected in addition to those corresponding to known tropomyosins of striated muscle. One of these was also detected in the leg muscle of 12 day-old mice. The identities of these species are uncertain, but they may correspond to alternatively spliced products of the same RNA transcripts that give rise to the predominant tropomyosin isoforms of striated muscle.
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