|  Help  |  About  |  Contact Us

Protein Coding Gene : Fgf10 fibroblast growth factor 10

Primary Identifier  MGI:1099809 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  14165
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Enables chemoattractant activity. Involved in positive regulation of DNA-templated transcription and radial glial cell differentiation. Acts upstream of or within several processes, including gland morphogenesis; lung development; and regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study intestinal atresia and lacrimoauriculodentodigital syndrome 1. Human ortholog(s) of this gene implicated in aplasia of lacrimal and salivary glands and lacrimoauriculodentodigital syndrome 3. Orthologous to human FGF10 (fibroblast growth factor 10).
PHENOTYPE: Homozygous mutants die at birth with multiple abnormalities including absence of lungs, severely truncated limbs, open eyelids, incomplete external genitalia, arrested pancreatic development, lack of mammary glands and impaired epidermal development. [provided by MGI curators]
  • synonyms:
  • FGF-10,
  • expressed sequence BB213776,
  • MGI:2145479,
  • Gsfaey17,
  • gsf abnormal eyes 17,
  • MGI:3529962,
  • fibroblast growth factor 10,
  • AEY17,
  • BB213776,
  • Fgf10

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

3 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

36 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For