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Publication : Mapping of human interferon regulatory factor 3 (IRF3) to chromosome 19q13.3-13.4 by an intragenic polymorphic marker.

First Author  Bellingham J Year  1998
Journal  Ann Hum Genet Volume  62
Issue  Pt 3 Pages  231-4
PubMed ID  9803267 Mgi Jnum  J:62618
Mgi Id  MGI:1859178 Doi  10.1046/j.1469-1809.1998.6230231.x
Citation  Bellingham J, et al. (1998) Mapping of human interferon regulatory factor 3 (IRF3) to chromosome 19q13.3-13.4 by an intragenic polymorphic marker. Ann Hum Genet 62(Pt 3):231-4
abstractText  We have identified a highly polymorphic intragenic marker composed of two dinucleotide repeats in an intron of the human interferon regulatory factor (IRF3) gene. This polymorphic marker has allowed us to map IRF3 to the boundary of 19q13.3-13.4 between the polymorphic markers D19S604 and D19S206 close to KLK1. An intron is present in a homologous position in the mouse Irf3 gene, but lacks the dinucleotide repeats present in the human intron. Syntenic conservation between this region of 19q13.3-13.4 maps Irf3 to either mouse chromosome 7 or 17.
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