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Allele : Gabbr1<tm1Bet> gamma-aminobutyric acid type B receptor subunit 1; targeted mutation 1, Bernhard Bettler
Primary Identifier  MGI:2159352 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gabbr1
Transmission  Germline Strain of Origin  BALB/c
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing exons 7-10. In situ hybridization experiments on brain sections of homozygous mice confirmed that no detectable transcript was produced from this allele. Western blot and radiolabeled binding assays confirmed that no functional protein was expressed in brain of homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • GB1<->,
  • GABAB(1)<->,
  • GABAB(1)<->,
  • GB1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

31 Publication categories

Trail: Allele




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