| Primary Identifier | MGI:7524438 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Prlhr |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISRP/Cas9 technology generated CCG to TCG change resulting in a proline to serine substitution at amino acid 193 (p.P193S). A second silent C to T mutation was also introduced to cause a loss of an Eagl restriction site for screening. The p.P193S is a rare loss of function variant identified in an individual with severe obesity. |
