| First Author | Hata A | Year | 1980 |
| Journal | Chem Biol Interact | Volume | 32 |
| Issue | 1-2 | Pages | 29-39 |
| PubMed ID | 7428115 | Mgi Jnum | J:31034 |
| Mgi Id | MGI:78360 | Doi | 10.1016/0009-2797(80)90066-6 |
| Citation | Hata A, et al. (1980) Acute cadmium intoxication in inbred mice: a study on strain differences. Chem Biol Interact 32(1-2):29-39 |
| abstractText | Male C3H, BALB/c and DBA/2 mice were injected subcutaneously with a single dose of 30 mumol CdCl2/kg. Most of the C3H mice died within 15 h, while all of DBA/2 survived for at least 48 h. At 6 h after Cd-injection, histology revealed severe hemorrhage, fatty change, zonal hepatocyte necrosis and congestion of C3H livers, while these findings were rare in the other strains even at 48 h post-injection. The rate of metallothionein (MT) induction at 6 h was significantly lower in C3H mice than in the other two strains. |
