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Protein Coding Gene : Slc46a2 solute carrier family 46, member 2

Primary Identifier  MGI:1353616 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  30936
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable cyclic-GMP-AMP transmembrane transporter activity. Acts upstream of or within several processes, including T cell homeostasis; negative regulation of T cell apoptotic process; and thymus development. Located in cell surface. Is expressed in several structures, including foregut gland; hemolymphoid system; and skin. Orthologous to human SLC46A2 (solute carrier family 46 member 2).
PHENOTYPE: About one-third of homozygotes carrying a reporter allele that results in a small deletion within exon 1 display a slight reduction in total thymocyte yield at 6 weeks of age. [provided by MGI curators]
  • synonyms:
  • Tscot,
  • Slc46a2,
  • RIKEN cDNA 5430429N04 gene,
  • MGI:1914810,
  • 5430429N04Rik,
  • thymic stromal cotransporter,
  • solute carrier family 46, member 2,
  • TSO-1C12,
  • Ly110

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