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Protein Coding Gene : Faap20 Fanconi anemia core complex associated protein 20

Primary Identifier  MGI:1914763 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  67513
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and ubiquitin-modified protein reader activity. Predicted to be involved in interstrand cross-link repair and translesion synthesis. Predicted to act upstream of or within DNA repair. Predicted to be located in cell junction; chromosome; and nuclear body. Predicted to be part of Fanconi anaemia nuclear complex and chromatin. Is expressed in several structures, including genitourinary system; immune system; liver; lung; and muscle tissue. Orthologous to human FAAP20 (FA core complex associated protein 20).
PHENOTYPE: Homozygous null mice show seminiferous tubule and ovarian follicle degeneration, small litter sizes, and increased sensitivity to DNA crosslinkers. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2610002J02 gene,
  • Fanconi anemia core complex associated protein 20,
  • Faap20,
  • 2610002J02Rik

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For