| Primary Identifier | MGI:7262689 | Allele Type | Transgenic |
| Attribute String | Dominant negative, Humanized sequence, Inserted expressed sequence | Gene | Tg(KRT18*R89C)22Rgo |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This transgene consists of the human keratin 18 cDNA containing an arginine to cysteine substitution at amino acid 89 in exon 1. Three lines were generated; F22, F30, and F50. The transgene copy number for line F22 is 10. The relative protein ratio of endogenous mouse Krt18 to over-expressed human KRT18 is 1:2. |
