Primary Identifier | MGI:98270 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 231691 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ammonia-lyase activity; protein homodimerization activity; and pyridoxal phosphate binding activity. Predicted to be involved in carboxylic acid metabolic process and protein-containing complex assembly. Predicted to act upstream of or within gluconeogenesis and lipid metabolic process. Predicted to be located in cytosol and mitochondrion. Is expressed in several structures, including genitourinary system; immune system; liver; musculature; and stomach. Orthologous to human SDS (serine dehydratase). PHENOTYPE: Sds is the serine dehydratase structural gene. Albino region deletions profoundly affect development and expression of some gluconeogenic enzymes, including Sds. In these deletion mice, Sds is expressed normally on the constitutive level, but fails to develop hormone-inducible expression. [provided by MGI curators] |