| Primary Identifier | MGI:6459753 | Allele Type | Transgenic |
| Attribute String | Dominant negative, Epitope tag, Humanized sequence, Inserted expressed sequence | Gene | Tg(CAG-EPM2A*C266S)1Bmin |
| Strain of Origin | C57BL/6 x SJL | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The human EPM2A cDNA containing a DSP-inactivating point mutation of a G to C change at position 797 resulting in a cysteine to serine substitution at amino acid 266 (p.C266S) with a c-myc tag at the 5' end is under the control of the CAG promoter (consisting of the cytomegalovirus immediate-early enhancer and the chicken beta-actin promoter). Two lines were generated. This line shows transgene expression in the brain, skeletal muscle, heart and liver. |
