Primary Identifier | MGI:3783463 | Allele Type | Chemically induced (ENU) |
Gene | Oca2 | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false | Project Collection | Beutler Mutagenetix |
molecularNote | The quicksilver mutation corresponds to a G-to-A transition at nucleotide position 1487, in the 14th of 24 total exons, resulting in replacement of glutamic acid by lysine at amino acid position 453 of the protein (E453K), in a highly conserved lumenal segment between the 5th and 6th transmembrane domains. |