| Primary Identifier | MGI:1923411 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 76161 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in presynaptic modulation of chemical synaptic transmission. Located in several cellular components, including dendrite membrane; endosome; and growth cone membrane. Is active in GABA-ergic synapse and synaptic vesicle. Is expressed in several structures, including alimentary system; central nervous system; sensory organ; vertebral axis musculature; and vibrissa. Orthologous to human LAMP5 (lysosomal associated membrane protein family member 5). PHENOTYPE: Homozygous null mice show increased susceptibility to PTZ-induced seizures, distinct interneuron loss, dystrophic neurites, delayed habituation in the open field and neuronal network deficits. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
