|  Help  |  About  |  Contact Us

Allele : Tg(Ttr-Hfe*C294Y)1Nca transgene insertion 1, Nancy C Andrews

Primary Identifier  MGI:4948233 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Ttr-Hfe*C294Y)1Nca
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false
molecularNote  The promoter drives hepatocyte-specific of the mouse cDNA with nucleotide substitutions that results in the amino acid substitution of tyrosine for cysteine at position 294 (C294Y). This mutation correspond to the human C282Y disease-causing mutation.
  • mutations:
  • Insertion
  • synonyms:
  • Hfe<C294Y>,
  • Hfe<C294Y>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele