Primary Identifier | MGI:4948233 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Ttr-Hfe*C294Y)1Nca |
Strain of Origin | C57BL/6NCrl | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The promoter drives hepatocyte-specific of the mouse cDNA with nucleotide substitutions that results in the amino acid substitution of tyrosine for cysteine at position 294 (C294Y). This mutation correspond to the human C282Y disease-causing mutation. |