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Allele : Casp4<tm1Yuan> caspase 4, apoptosis-related cysteine peptidase; targeted mutation 1, Junying Yuan

Primary Identifier  MGI:2159366 Allele Type  Targeted
Attribute String  Null/knockout Gene  Casp4
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced a 1.5 kb genomic fragment containing sequences encoding 16 amino acids of the active site. Western blot analysis on lysates derived from spleen of both LPS-injected and control homozygous mice confirmed that no detectable protein is expressed from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Casp11<->,
  • Casp11<->,
  • casp-11,
  • casp-11,
  • Caspase-11-,
  • Caspase-11-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

63 Publication categories

Trail: Allele