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Publication : mtDNA phylogeny and evolution of laboratory mouse strains.

First Author  Goios A Year  2007
Journal  Genome Res Volume  17
Issue  3 Pages  293-8
PubMed ID  17284675 Mgi Jnum  J:149204
Mgi Id  MGI:3847883 Doi  10.1101/gr.5941007
Citation  Goios A, et al. (2007) mtDNA phylogeny and evolution of laboratory mouse strains. Genome Res 17(3):293-8
abstractText  Inbred mouse strains have been maintained for more than 100 years, and they are thought to be a mixture of four different mouse subspecies. Although genealogies have been established, female inbred mouse phylogenies remain unexplored. By a phylogenetic analysis of newly generated complete mitochondrial DNA sequence data in 16 strains, we show here that all common inbred strains descend from the same Mus musculus domesticus female wild ancestor, and suggest that they present a different mitochondrial evolutionary process than their wild relatives with a faster accumulation of replacement substitutions. Our data complement forthcoming results on resequencing of a group of priority strains, and they follow recent efforts of the Mouse Phenome Project to collect and make publicly available information on various strains.
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