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Protein Domain : 8-oxoguanine DNA-glycosylase

Primary Identifier  IPR004577 Type  Family
Short Name  Ogg1
description  One of the major base lesions induced by oxidative stress is 8-oxoguanine (8-oxoG), one of the oxidised forms of guanine. 8-oxoguanine DNA glycosylase (also known as N-glycosylase/DNA lyase) functions in base excision repair and is responsible for the excision of 8-oxoguanine. It has beta-lyase activity thatnicks DNA 3' to the lesion [, , ].

0 Child Features

0 Parent Features

2 Protein Domain Regions