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Allele : Acp2<tm1Psa> acid phosphatase 2, lysosomal; targeted mutation 1, Paul Saftig

Primary Identifier  MGI:2180084 Allele Type  Targeted
Attribute String  Null/knockout Gene  Acp2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene was inserted into exon 7, introducing a translational stop codon into the open reading frame. Northern blot analysis showed an absence of expression in the livers and kidneys of homozygous mice. No enzymatic activity was detected in assays of kidney and spleen homogenates from homozygotes.
  • mutations:
  • Insertion
  • synonyms:
  • LAP<->,
  • LAP<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele