Primary Identifier | MGI:5488498 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Tlr7)6Boll |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The RP23-139P21 BAC construct that contains the Tlr7, Tlr8, and Tmsb4x genes, was replaced the first 83 kb with a neomycin cassette so that Tlr7 is be the only gene expressed. Six founder lines were produced with varying insert numbers and expression levels 4 to 16 fold greater than controls. This line has a 4- to 8-fold increase in expression. |