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Protein Domain : KMT2A, PHD domain 2

Primary Identifier  IPR042025 Type  Domain
Short Name  KMT2A_PHD2
description  This entry represents the second PHD domain of KMT2A.Histone-lysine N-methyltransferase 2A (KMT2A; ) is the catalytic subunit of the MLL1/MLL complex, mediating methylation of 'Lys-4' of histone H3 (H3K4me), a specific tag for epigenetic transcriptional activation []. KMT2A is processed by the threonine endopeptidase taspase, releasing products N320 and C180 []. KMT2A contains a CxxC (x for any residue) zinc finger domain, three plant homeodomain (PHD) fingers, a Bromodomain domain, an extended PHD (ePHD) finger, Cys2HisCys5HisCys2His, two FY (phenylalanine tyrosine)-rich domains, and a SET (Suppressor of variegation, Enhancer of zeste, Trithorax) domain.

0 Child Features

1 Parent Features

2 Protein Domain Regions