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Allele : Epas1<tm1Pec> endothelial PAS domain protein 1; targeted mutation 1, Peter Carmeliet

Primary Identifier  MGI:2663583 Allele Type  Targeted
Attribute String  Null/knockout Gene  Epas1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by replacement of exon 2 with a neomycin resistance cassette via homologous recombination. Exon 2 encodes the basic helix-loop-helix domain which is essential for DNA binding and dimerization.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Hif2alpha<->,
  • Hif2alpha<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories

Trail: Allele