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Publication : Expression of Six3 Opposite Strand (Six3OS) during mouse embryonic development.

First Author  Geng X Year  2007
Journal  Gene Expr Patterns Volume  7
Issue  3 Pages  252-7
PubMed ID  17084678 Mgi Jnum  J:116113
Mgi Id  MGI:3693019 Doi  10.1016/j.modgep.2006.09.007
Citation  Geng X, et al. (2007) Expression of Six3 Opposite Strand (Six3OS) during mouse embryonic development. Gene Expr Patterns 7(3):252-257
abstractText  Recently, sequence analyses have identified a large number of opposite strand transcripts in the vertebrate genome. Although the transcripts appear to be spliced and polyadenylated, many of them are predicted to represent noncoding RNAs. High levels of noncoding transcripts of the Six3 Opposite Strand (Six3OS) were recently identified in the embryonic and postnatal retina of the mouse. In this study, we expanded those initial expression analyses, elucidated in detail the developmental expression profile of mouse Six3OS in the brain and visual system, and compared it with that of Six3. Our results show that Six3OS expression overlaps extensively with that of Six3 and is not altered in Six3-null embryos.
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