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Publication : LOCATE: a mouse protein subcellular localization database.

First Author  Fink JL Year  2006
Journal  Nucleic Acids Res Volume  34
Issue  Database issue Pages  D213-7
PubMed ID  16381849 Mgi Jnum  J:106145
Mgi Id  MGI:3617675 Doi  10.1093/nar/gkj069
Citation  Fink JL, et al. (2006) LOCATE: a mouse protein subcellular localization database. Nucleic Acids Res 34(Database issue):D213-7
abstractText  We present here LOCATE, a curated, web-accessible database that houses data describing the membrane organization and subcellular localization of proteins from the FANTOM3 Isoform Protein Sequence set. Membrane organization is predicted by the high-throughput, computational pipeline MemO. The subcellular locations of selected proteins from this set were determined by a high-throughput, immunofluorescence-based assay and by manually reviewing >1700 peer-reviewed publications. LOCATE represents the first effort to catalogue the experimentally verified subcellular location and membrane organization of mammalian proteins using a high-throughput approach and provides localization data for approximately 40% of the mouse proteome. It is available at http://locate.imb.uq.edu.au.
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