Primary Identifier | MGI:2445840 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tfcp2 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = RW8. |
molecularNote | A portion of exon 1 and all of exon 2 was replaced by a hygromycin selection cassette inserted by homologous recombination. The insertion deleted sequence encoding the initiator methionine and the trans-activation domain and introduced a frameshift mutation into all reading frames. Transcript was undetected by both RNAse protection and RT-PCR analysis. |