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Publication : Transmission of SARS-CoV-2 via close contact and respiratory droplets among hACE2 mice.

First Author  Bao L Year  2020
Journal  J Infect Dis PubMed ID  32444876
Mgi Jnum  J:288244 Mgi Id  MGI:6431164
Doi  10.1093/infdis/jiaa281 Citation  Bao L, et al. (2020) Transmission of SARS-CoV-2 via close contact and respiratory droplets among hACE2 mice. J Infect Dis
abstractText  We simulated three transmission modes including close contact, respiratory droplets and aerosol routes in labratory. SARS-CoV-2 can be highly transmitted among naive hACE2 mice via close contact because 7/13 naive hACE2 mice were SARS-CoV-2 antibodies seropositivity on 14 days after introduced into the same cage with 3 infected-hACE2 mice. For respiratory droplets, SARS-CoV-2 antibodies from 3/10 naive hACE2 mice showed seropositivity on 14 days after introduced into the grids separated same cage from 3 infected-hACE2 mice. Additionally, hACE2 mice cannot be experimentally infected via aerosol inoculation until continued up to 25 min with high virus concentrations.
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