| First Author | Kelly CL | Year | 1993 |
| Journal | Genomics | Volume | 18 |
| Issue | 1 | Pages | 137-40 |
| PubMed ID | 8276399 | Mgi Jnum | J:15135 |
| Mgi Id | MGI:63272 | Doi | 10.1006/geno.1993.1438 |
| Citation | Kelly CL, et al. (1993) Cloning and characterization of the mouse short-chain acyl-CoA dehydrogenase cDNA. Genomics 18(1):137-40 |
| abstractText | Short-chain acyl-CoA dehydrogenase (SCAD) is one of five homologous dehydrogenases that catalyze the first reaction in the beta-oxidation of fatty acids. As the name implies, the substrate for this enzyme is short-chain acyl-CoA (C4-C6). We report here the coding and 3'UT sequence of the cDNA for mouse precursor SCAD. The mouse SCAD cDNA coding sequence covers 1239 bp. This represents a 24-amino-acid leader peptide and a 388-amino-acid mature peptide. Comparison of this sequence with reported rat and human SCAD cDNA sequences reveals a high degree of homology among the three species. Comparison of the amino acid sequence with that of other acyl-CoA dehydrogenases, medium-chain acyl-CoA dehydrogenase and long-chain acyl-CoA dehydrogenase, also shows a high degree of homology. |
