| Primary Identifier | MGI:97547 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 18641 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables 6-phosphofructokinase activity. Involved in glycolytic process through fructose-6-phosphate. Acts upstream of or within several processes, including carbohydrate phosphorylation; fructose 6-phosphate metabolic process; and negative regulation of insulin secretion. Located in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Orthologous to human PFKL (phosphofructokinase, liver type). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete preweaning lethality. Female heterozygous mice show anomalies in the hair cycle catagen phase and hair follicle degeneration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
