Primary Identifier | MGI:6199978 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Aicda |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced G to A transition at base pair 122,561,867 (v38) on chromosome 6, or base pair 8,059 in the GenBank genomic region NC_000072 encoding Aicda. The mutation corresponds to residue 547 in the mRNA sequence NM_009645 within exon 4 of 5 total exons. The mutation results in a valine to isoleucine substitution at residue 152 (V152I) in the AID protein. |