| Primary Identifier | MGI:1915206 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 67956 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable histone H4K20 methyltransferase activity and transcription corepressor activity. Predicted to be involved in negative regulation of double-strand break repair via homologous recombination; negative regulation of transcription by RNA polymerase II; and regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to act upstream of or within cell division; chromatin organization; and methylation. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of chromatin. Predicted to be active in nucleus and polytene chromosome. Is expressed in several structures, including extraembryonic component. Orthologous to human KMT5A (lysine methyltransferase 5A). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit embryonic lethality. Mice homozygous for an allele lacking exon 7 die prior to implantation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
