Primary Identifier | MGI:6433825 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Irf5 |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 3 to 9 were flanked by loxP sites (size of loxP-flanked region 4.2 kb). A polyadenylation signal (hGHpA: human Growth Hormone polyadenylation signal) has been inserted 3' of the gene in order to prevent downstream transcription. The conditional KO allele was obtained after Flp-mediated removal of the selection marker. |