| Primary Identifier | MGI:1349444 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 107766 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables 3-hydroxyanthranilate 3,4-dioxygenase activity. Predicted to be involved in several processes, including pyridine-containing compound biosynthetic process; response to cadmium ion; and response to zinc ion. Predicted to act upstream of or within pyridine nucleotide biosynthetic process. Predicted to be located in cytosol and mitochondrial membrane. Predicted to be active in cytoplasm. Is expressed in ductus deferens; epididymis; esophagus; metanephros; and testis. Orthologous to human HAAO (3-hydroxyanthranilate 3,4-dioxygenase). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced LPS-induced depressive behaviors and altered kynurenine metabolism. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
