First Author | Yang S | Year | 1996 |
Journal | FEMS Immunol Med Microbiol | Volume | 13 |
Issue | 2 | Pages | 141-5 |
PubMed ID | 8731022 | Mgi Jnum | J:33338 |
Mgi Id | MGI:80819 | Doi | 10.1016/0928-8244(95)00096-8 |
Citation | Yang S, et al. (1996) Infectivity of preserved Cryptosporidium parvum oocysts for immunosuppressed adult mice. FEMS Immunol Med Microbiol 13(2):141-5 |
abstractText | The present study was undertaken to determine the infectivity of Cryptosporidium parvum oocysts for immunosuppressed adult C57BL/6N mice after the oocysts had been stored from 1-48 months at 4 degrees C in 2.5% potassium dichromate. All mice inoculated with oocysts 1-18 months old developed patent infections, while mice inoculated with older oocysts remained uninfected. The prepatent period was extended from 2 to 6 or 7 days as the storage time for oocysts increased. The finding that C. parvum oocysts remain infective for mice for at least 18 months offers important economic and time-saving advantages for investigators who frequently require large numbers of oocysts that must be painstakingly purified from calf manure. |