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Protein Coding Gene : Ppp1r35 protein phosphatase 1, regulatory subunit 35

Primary Identifier  MGI:1922853 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  69871
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable phosphatase binding activity and protein phosphatase inhibitor activity. Involved in notochord morphogenesis and positive regulation of cilium assembly. Predicted to be located in centrosome. Predicted to be active in centriole. Is expressed in several structures, including alimentary system; central nervous system; egg cylinder; genitourinary system; and hemolymphoid system. Orthologous to human PPP1R35 (protein phosphatase 1 regulatory subunit 35).
PHENOTYPE: Mice homozygous for a knock-out allele show embryonic growth retardation, failure of embryo turning, distended pericardium, increased neural tube cell death, and embryonic lethality during early organogenesis. [provided by MGI curators]
  • synonyms:
  • MGI:2141018,
  • 2010007H12Rik,
  • RIKEN cDNA 2010011D20 gene,
  • Ppp1r35,
  • AL024004,
  • MGI:1917121,
  • expressed sequence AL024004,
  • 2010011D20Rik,
  • protein phosphatase 1, regulatory subunit 35,
  • RIKEN cDNA 2010007H12 gene

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