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Publication : HSF1 in Translation.

First Author  de Billy E Year  2013
Journal  Cancer Cell Volume  24
Issue  2 Pages  147-9
PubMed ID  23948296 Mgi Jnum  J:202610
Mgi Id  MGI:5520114 Doi  10.1016/j.ccr.2013.07.017
Citation  de Billy E, et al. (2013) HSF1 in Translation. Cancer Cell 24(2):147-9
abstractText  The master regulator of the classical cytoprotective "heat shock" response, heat shock factor 1 (HSF1), is increasingly implicated in cancer pathogenesis, but the mechanisms remain poorly understood. A recent study connects increased protein translation to activation of HSF1 in malignant cells and demonstrates the therapeutic benefit of targeting this link.
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