First Author | de Billy E | Year | 2013 |
Journal | Cancer Cell | Volume | 24 |
Issue | 2 | Pages | 147-9 |
PubMed ID | 23948296 | Mgi Jnum | J:202610 |
Mgi Id | MGI:5520114 | Doi | 10.1016/j.ccr.2013.07.017 |
Citation | de Billy E, et al. (2013) HSF1 in Translation. Cancer Cell 24(2):147-9 |
abstractText | The master regulator of the classical cytoprotective "heat shock" response, heat shock factor 1 (HSF1), is increasingly implicated in cancer pathogenesis, but the mechanisms remain poorly understood. A recent study connects increased protein translation to activation of HSF1 in malignant cells and demonstrates the therapeutic benefit of targeting this link. |