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Allele : Tg(SFTPC-CCNE1*T62A*T380A)4Edm transgene insertion 4, Ethan Dmitrovsky

Primary Identifier  MGI:3760420 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(SFTPC-CCNE1*T62A*T380A)4Edm
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  A "degradation resistant" human cyclin E cDNA was placed under the control of the human surfactant protein C promoter which causes expression in alveolar type II and bronchioalveolar cells. The protein expressed by this transgenes has a threonine for alanine substitution at amino acid residues 62 and 380. Transgenic protein was detected immunologically.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele