| Primary Identifier | MGI:5806089 | Allele Type | Targeted |
| Attribute String | Conditional ready, Inserted expressed sequence, Reporter | Gene | Tcf3 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 13. A neomycin resistance cassette, loxP site, human PBX1a, IRES and EGFP reporter gene were inserted downstream of exon 16. Cre-mediated recombination is required to remove exons 13 through 16 and produce a fusion between the endogenous gene and inserted human sequence. This fusion replicates the t(1;19) chromosomal translocation present in some pediatric acute lymphoblastic leukemia patients. |
