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Publication : Refined radiation hybrid map of mouse chromosome 17.

First Author  Schalkwyk LC Year  1998
Journal  Mamm Genome Volume  9
Issue  10 Pages  807-11
PubMed ID  9745034 Mgi Jnum  J:50196
Mgi Id  MGI:1290017 Doi  10.1007/s003359900871
Citation  Schalkwyk LC, et al. (1998) Refined radiation hybrid map of mouse chromosome 17. Mamm Genome 9(10):807-11
abstractText  We have made a radiation hybrid map of mouse Chromosome (Chr) 17 with 75 microsatellite markers, including those from McCarthy et al. (Genome Res 7, 1153-1161, 1997). Seventy-four of the markers are linked at LOD > 9, and all link at LOD > 5. A LOD 3 framework of 18 markers was used to construct a placement map. The order obtained is in good agreement with genetic maps, and distance estimates give an idea of how recombination rates vary across the chromosome. Recombination is remarkably low with respect to RH break frequency in the region from the centromere to the end of H2. This is similar in interspecific and intersubspecific crosses despite the inversion of a substantial part of this region in Mus spretus with respect to Mus musculus.
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