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Publication : Chronic infection of Balb/c mice with murine herpesvirus 72 is associated with neoplasm development.

First Author  Mistríkóva J Year  1996
Journal  Acta Virol Volume  40
Issue  5-6 Pages  297-301
PubMed ID  9171459 Mgi Jnum  J:39402
Mgi Id  MGI:86784 Citation  Mistrikova J, et al. (1996) Chronic infection of Balb/c mice with murine herpesvirus 72 is associated with neoplasm development. Acta Virol 40(5-6):297-301
abstractText  One hundred Balb/c mice were infected with murine herpesvirus strain 72 (MHV-72) and observed for 2.5 years for neoplasm development and virus presence in tumour as well as non-tumour tissues. Out of 13 neoplasm-bearing mice the virus was recovered from solid tumours (one lymphoma, two non-differentiated lymphoblastomas and two fibrosarcomas) of five mice and from the spleen of one mouse with lymphatic leukemia. The virus persisted frequently also in various organs of the neoplasm-bearing mice.
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