Primary Identifier | MGI:95286 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 13626 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in facultative heterochromatin formation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; regulation of adaxial/abaxial pattern formation; and regulation of gene expression. Located in pronucleus. Part of ESC/E(Z) complex; chromatin silencing complex; and sex chromatin. Is expressed in several structures, including branchial arch; central nervous system; early embryo; embryo mesenchyme; and urinary system. Orthologous to human EED (embryonic ectoderm development). PHENOTYPE: Homozygous mutant mice are dwarfed and their coat color is dilute. [provided by MGI curators] |