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Protein Coding Gene : Mterf1a mitochondrial transcription termination factor 1a

Primary Identifier  MGI:1918240 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  545725
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable double-stranded DNA binding activity. Predicted to be involved in DNA geometric change and termination of mitochondrial transcription. Located in mitochondrion. Orthologous to human MTERF1 (mitochondrial transcription termination factor 1).
PHENOTYPE: Mice homozygous for a knock-out allele of both Mterf1a and Mterf1b exhibit impaired transcription initiation at light-strand promoters resulting in a decrease of de novo transcription and reduced 7S RNA. [provided by MGI curators]
  • synonyms:
  • Mterf1a,
  • mitochondrial transcription termination factor 1a,
  • 9230106K09Rik,
  • Mterf1,
  • RIKEN cDNA 4931431L11 gene,
  • RIKEN cDNA 9230106K09 gene,
  • Mterf,
  • MGI:1925325,
  • 4931431L11Rik

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