| Primary Identifier | MGI:107247 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 11500 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables endopeptidase activity. Involved in several processes, including epididymis development; positive regulation of flagellated sperm motility; and positive regulation of sperm capacitation. Located in plasma membrane. Orthologous to human ADAM7 (ADAM metallopeptidase domain 7). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced male fertility with decreased cell height in caput epididymis, spermatic granuloma, kinked sperm flagellum and reduced sperm motility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
