Primary Identifier | MGI:5829767 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Kif1a |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site flanked beta-geo (lacZ (beta-galactosidase) and neomycin resistance gene fusion) cassette was inserted into the intron upstream of exon P. A further loxP site was inserted into the intron downstream of exon P+2. These P exons encode ATP-binding P loops. Subsequent cre-mediated recombination created this conditional-ready allele, with the beta-geo cassette removed and the targeted exons P, P+1 and P+2, remaining floxed. |