Primary Identifier | MGI:1923452 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 70546 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables protein-cysteine S-myristoyltransferase activity; protein-cysteine S-palmitoyltransferase activity; and protein-cysteine S-stearoyltransferase activity. Involved in protein localization to membrane raft; protein localization to plasma membrane; and synapse assembly. Located in plasma membrane and recycling endosome membrane. Is active in postsynaptic recycling endosome. Is expressed in several structures, including early conceptus; genitourinary system; nervous system; pancreas tip epithelium; and retina. Orthologous to human ZDHHC2 (zinc finger DHHC-type palmitoyltransferase 2). PHENOTYPE: Mice homozygous for a null allele exhibit decreased susceptibility to imiquimod-induced psoriasis. [provided by MGI curators] |