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Comment :

Type  MGI:General Description  at 2 months, mutant livers appear a little darker in color, with areas of focal dysplasia and reduced glycogen storage in the parenchyma; no steatosis is observed at 6- to 12-months of age, mutant livers display multiple hyperplastic pale nodules scattered throughout all lobes by 12 months, the normal lobular structure is disrupted; hyperplastic nodules consist of highly vacuolated cells that compress the adjacent normal tissue, in the absence of fibrosis