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Protein Coding Gene : Fgf1 fibroblast growth factor 1

Primary Identifier  MGI:95515 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  14164
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable several functions, including Hsp70 protein binding activity; S100 protein binding activity; and signaling receptor binding activity. Acts upstream of or within several processes, including organ induction; positive regulation of epithelial cell proliferation; and positive regulation of nitrogen compound metabolic process. Located in extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in brain ischemia; cleft lip; myocardial infarction; schizophrenia; and urinary bladder cancer. Orthologous to human FGF1 (fibroblast growth factor 1).
PHENOTYPE: Mice homozygous for a knock-out allele are viable, breed and develop normally, and exhibit normal brain structure and normal rates of wound healing. [provided by MGI curators]
  • synonyms:
  • fibroblast growth factor, acidic,
  • Fgfa,
  • fibroblast growth factor 1,
  • Fgf1,
  • Fgf-1,
  • MGD-MRK-9760,
  • MGD-MRK-9773,
  • fibroblast growth factor 1 (acidic),
  • MGD-MRK-9766

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

55 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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1 Driver For