|  Help  |  About  |  Contact Us

Protein Coding Gene : Heyl hairy/enhancer-of-split related with YRPW motif-like

Primary Identifier  MGI:1860511 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  56198
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Involved in several processes, including heart development; nephron development; and regulation of transcription by RNA polymerase II. Acts upstream of or within epithelial to mesenchymal transition involved in endocardial cushion formation; negative regulation of gene expression; and skeletal muscle cell differentiation. Located in cytoplasm. Is expressed in several structures, including cardiovascular system; embryo mesenchyme; inner ear; nervous system; and urinary system. Orthologous to human HEYL (hes related family bHLH transcription factor with YRPW motif like).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced TrkC+ sensory neurons in the dorsal root ganglia. [provided by MGI curators]
  • synonyms:
  • Hrt3,
  • hairy/enhancer-of-split related with YRPW motif-like,
  • Heyl,
  • bHLHb33,
  • Hesr3,
  • MGI:1353482,
  • Hey3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For