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Protein Domain : Galactose-binding domain-like

Primary Identifier  IPR040502 Type  Domain
Short Name  GalBD-like
description  Proteins containing a galactose-binding domain-like fold can be found in several different protein families, in both eukaryotes and prokaryotes. The common function of these domains is to bind to specific ligands, such as cell-surface-attached carbohydrate substrates for galactose oxidase and sialidase [], phospholipids on the outer side of the mammalian cell membrane for coagulation factor Va [], membrane-anchored ephrin for the Eph family of receptor tyrosine kinases [], and a complex of broken single-stranded DNA and DNA polymerase beta for XRCC1 []. The structure of the galactose-binding domain-like members consists of a β-sandwich, in which the strands making up the sheets exhibit a jellyroll fold [].This entry represents a galactose-binding domain-like fold domain found in endo-alpha-N-acetylgalactosaminidases from bacteria.

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0 Protein Domain Regions