Type | MGI:Normal | Description | mutant macrophages exhibited a normal TNF response to signaling via other toll-like receptor (TLR) ligands: the TLR2/1 ligand Pam3CSK4 (triacyl lipopeptide); the TLR4 ligand lipopolysaccharide (LPS); the TLR9 ligand CpG-DNA (single-stranded DNA); the TLR7 ligand resiquimod/R-848 (single-stranded RNA mimetic); and the TLR3 ligand poly I:C (double-stranded RNA) |