Primary Identifier | MGI:1914111 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 66861 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables several functions, including ATPase activator activity; ATPase binding activity; and oxidoreductase activity, acting on a sulfur group of donors. Predicted to be involved in several processes, including IRE1-mediated unfolded protein response; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; and protein folding in endoplasmic reticulum. Located in endoplasmic reticulum. Orthologous to human DNAJC10 (DnaJ heat shock protein family (Hsp40) member C10). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased endoplasmic reticulum stress in the salivary gland. Female homozygous mutant mice are smaller than controls. [provided by MGI curators] |