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Protein Domain : AP-4 complex accessory subunit Tepsin

Primary Identifier  IPR039273 Type  Family
Short Name  TEPSIN
description  Tepsin associates with the adapter-like complex (AP-4) complex, which forms a non-clathrin coat around cytoplasmic vesicles in plants and animals []. Mutagenesis studies have identified two phylogenetically conserved peptide motifs within the C terminus of tepsin that interact with the C-terminal ear (or appendage) domains of the beta4 and epsilon subunits of AP-4 []. The homologue from Arabidopsis thaliana is known as MTV1 (At3g16270), which mediates clathrin-dependent trafficking of vacuolar cargo from the trans-Golgi network [].

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5 Protein Domain Regions